EVE: Online Custom Character Creator
The male character creator running in the engine. If you download the EVE: Online demo, you can play with the character creator yourself to see how fluid and fun it is.

 
 

The character creator modifications are done with blendshapes, but my duties were developing the underlying skeleton structure for the facial animation as well as making sure the mesh topology could handle the deformation during extensive sculpting. The joints positions were adjusted with the blendshapes so that the animation would still work properly. This allowed for a ton of flexibility, so much so, we had a contest to see if fans could recreate famous faces. Here are some examples of some of the best ones. Remember, this is fan art, not professional artists.

Vigfus (CCP tech artist) did a write up on how the specifics of the character creator mesh deformation was handled in a CCP Development Blog post. Click pic for the post.